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Sang CC, Moore G, Tereshchenko M, Nosella ML, Zhang H, Alderson TR, Dasovich M, Leung A, Finkelstein IJ, Forman-Kay JD, Lee HO (2024)
PARP1 condensates differentially partition DNA repair proteins and enhance DNA ligation.
bioRxiv : the preprint server for biology
DOI: 10.1101/2024.01.20.575817, PubMed: 38328070

Sever AIM, Alderson TR, Rennella E, Aramini JM, Liu ZH, Harkness RW, Kay LE (2023)
Activation of caspase-9 on the apoptosome as studied by methyl-TROSY NMR.
Proceedings of the National Academy of Sciences of the United States of America, Issue 51, Vol. 120, e2310944120
DOI: 10.1073/pnas.2310944120, PubMed: 38085782

Alderson TR, Pritišanac I, Kolarić Đ, Moses AM, Forman-Kay JD (2023)
Systematic identification of conditionally folded intrinsically disordered regions by AlphaFold2.
Proceedings of the National Academy of Sciences of the United States of America, Issue 44, Vol. 120, e2304302120
DOI: 10.1073/pnas.2304302120, PubMed: 37878721

Spreitzer E, Alderson TR, Bourgeois B, Eggenreich L, Habacher H, Brahmersdorfer G, Pritišanac I, Sánchez-Murcia PA, Madl T (2022)
FOXO transcription factors differ in their dynamics and intra/intermolecular interactions.
Current research in structural biology, Vol. 4, 118-133
DOI: 10.1016/j.crstbi.2022.04.001, PubMed: 35573459

Alderson TR, Adriaenssens E, Asselbergh B, Pritišanac I, Van Lent J, Gastall HY, Wälti MA, Louis JM, Timmerman V, Baldwin AJ, Lp Benesch J (2021)
A weakened interface in the P182L variant of HSP27 associated with severe Charcot-Marie-Tooth neuropathy causes aberrant binding to interacting proteins.
The EMBO journal, Issue 8, Vol. 40, e103811
DOI: 10.15252/embj.2019103811, PubMed: 33644875

Alderson TR, Kay LE (2021)
NMR spectroscopy captures the essential role of dynamics in regulating biomolecular function.
Cell, Issue 3, Vol. 184, 577-595
DOI: 10.1016/j.cell.2020.12.034, PubMed: 33545034

Pritišanac I, Alderson TR, Güntert P (2020)
Automated assignment of methyl NMR spectra from large proteins.
Progress in nuclear magnetic resonance spectroscopy, Vol. 118-119, 54-73
DOI: 10.1016/j.pnmrs.2020.04.001, PubMed: 32883449

Ramanujam V, Alderson TR, Pritišanac I, Ying J, Bax A (2020)
Protein structural changes characterized by high-pressure, pulsed field gradient diffusion NMR spectroscopy.
Journal of magnetic resonance (San Diego, Calif. : 1997), Vol. 312, 106701
DOI: 10.1016/j.jmr.2020.106701, PubMed: 32113145

Alderson TR, Ying J, Bax A, Benesch JLP, Baldwin AJ (2020)
Conditional Disorder in Small Heat-shock Proteins.
Journal of molecular biology, Issue 9, Vol. 432, 3033-3049
DOI: 10.1016/j.jmb.2020.02.003, PubMed: 32081587

Alderson TR, Kay LE (2020)
Unveiling invisible protein states with NMR spectroscopy.
Current opinion in structural biology, Vol. 60, 39-49
DOI: 10.1016/j.sbi.2019.10.008, PubMed: 31835059

Pritišanac I, Würz JM, Alderson TR, Güntert P (2019)
Automatic structure-based NMR methyl resonance assignment in large proteins.
Nature communications, Issue 1, Vol. 10, 4922
DOI: 10.1038/s41467-019-12837-8, PubMed: 31664028

Collier MP, Alderson TR, de Villiers CP, Nicholls D, Gastall HY, Allison TM, Degiacomi MT, Jiang H, Mlynek G, Fürst DO, van der Ven PFM, Djinovic-Carugo K, Baldwin AJ, Watkins H, Gehmlich K, Benesch JLP (2019)
HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C.
Science advances, Issue 5, Vol. 5, eaav8421
DOI: 10.1126/sciadv.aav8421, PubMed: 31131323

Alderson TR, Roche J, Gastall HY, Dias DM, Pritišanac I, Ying J, Bax A, Benesch JLP, Baldwin AJ (2019)
Local unfolding of the HSP27 monomer regulates chaperone activity.
Nature communications, Issue 1, Vol. 10, 1068
DOI: 10.1038/s41467-019-08557-8, PubMed: 30842409

Charlier C, Courtney JM, Alderson TR, Anfinrud P, Bax A (2018)
Monitoring 15N Chemical Shifts During Protein Folding by Pressure-Jump NMR.
Journal of the American Chemical Society, Issue 26, Vol. 140, 8096-8099
DOI: 10.1021/jacs.8b04833, PubMed: 29923716

Charlier C, Alderson TR, Courtney JM, Ying J, Anfinrud P, Bax A (2018)
Study of protein folding under native conditions by rapidly switching the hydrostatic pressure inside an NMR sample cell.
Proceedings of the National Academy of Sciences of the United States of America, Issue 18, Vol. 115, E4169-E4178
DOI: 10.1073/pnas.1803642115, PubMed: 29666248

Alderson TR, Lee JH, Charlier C, Ying J, Bax A (2018)
Propensity for cis-Proline Formation in Unfolded Proteins.
Chembiochem : a European journal of chemical biology, Issue 1, Vol. 19, 37-42
DOI: 10.1002/cbic.201700548, PubMed: 29064600

Alderson TR, Charlier C, Torchia DA, Anfinrud P, Bax A (2017)
Monitoring Hydrogen Exchange During Protein Folding by Fast Pressure Jump NMR Spectroscopy.
Journal of the American Chemical Society, Issue 32, Vol. 139, 11036-11039
DOI: 10.1021/jacs.7b06676, PubMed: 28766333

Pritišanac I, Degiacomi MT, Alderson TR, Carneiro MG, Ab E, Siegal G, Baldwin AJ (2017)
Automatic Assignment of Methyl-NMR Spectra of Supramolecular Machines Using Graph Theory.
Journal of the American Chemical Society, Issue 28, Vol. 139, 9523-9533
DOI: 10.1021/jacs.6b11358, PubMed: 28691806

Alderson TR, Benesch JLP, Baldwin AJ (2017)
Proline isomerization in the C-terminal region of HSP27.
Cell stress & chaperones, Issue 4, Vol. 22, 639-651
DOI: 10.1007/s12192-017-0791-z, PubMed: 28547731

Alderson TR, Bax A (2016)
Parkinson's disease: Disorder in the court.
Nature, Issue 7588, Vol. 530, 38-9
DOI: 10.1038/nature16871, PubMed: 26808901

Kim JH, Bothe JR, Alderson TR, Markley JL (2015)
Tangled web of interactions among proteins involved in iron-sulfur cluster assembly as unraveled by NMR, SAXS, chemical crosslinking, and functional studies.
Biochimica et biophysica acta, Issue 6, Vol. 1853, 1416-28
DOI: 10.1016/j.bbamcr.2014.11.020, PubMed: 25450980

Alderson TR, Kim JH, Cai K, Frederick RO, Tonelli M, Markley JL (2014)
The specialized Hsp70 (HscA) interdomain linker binds to its nucleotide-binding domain and stimulates ATP hydrolysis in both cis and trans configurations.
Biochemistry, Issue 46, Vol. 53, 7148-59
DOI: 10.1021/bi5010552, PubMed: 25372495

Kim JH, Alderson TR, Frederick RO, Markley JL (2014)
Nucleotide-dependent interactions within a specialized Hsp70/Hsp40 complex involved in Fe-S cluster biogenesis.
Journal of the American Chemical Society, Issue 33, Vol. 136, 11586-9
DOI: 10.1021/ja5055252, PubMed: 25080945

Alderson TR, Markley JL (2013)
Biophysical characterization of α-synuclein and its controversial structure.
Intrinsically disordered proteins, Issue 1, Vol. 1, 18-39
DOI: 10.4161/idp.26255, PubMed: 24634806