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Gaber T, Monecke T, Grabowski J, Simon B, Williams T, Roman V, Chao J, Hennig J, Ephrussi A, Niessing D, Heber S (2025)
A direct interaction between the RNA-binding proteins Staufen and Tm1-I/C in the oskar mRNA transport complex.
Cell reports, Issue 7, Vol. 44, 115906
DOI: 10.1016/j.celrep.2025.115906, PubMed: 40570376

Müller-Hermes C, Piomponi V, Hilber S, Asami S, Kreutz C, Bussi G, Sattler M (2025)
Unique conformational dynamics and protein recognition of A-to-I hyper-edited dsRNA.
Nucleic acids research, Issue 12, Vol. 53
DOI: 10.1093/nar/gkaf550, PubMed: 40568935

Walla B, Dietrich AM, Brames E, Bischoff D, Fritzsche S, Castiglione K, Janowski R, Niessing D, Weuster-Botz D (2025)
Application of a Rational Crystal Contact Engineering Strategy on a Poly(ethylene terephthalate)-Degrading Cutinase.
Bioengineering (Basel, Switzerland), Issue 6, Vol. 12
DOI: 10.3390/bioengineering12060561, PubMed: 40564377

Wilhelm A, Flynn C, Hammer E, Roessler J, Haller B, Napieralski R, Leuthner M, Tosheska S, Knoops K, Mathew A, Ciarimboli G, Kranich J, Flaskamp L, King S, Gevensleben H, Emslander Q, Pastucha A, Reisbeck M, Rief L, Bronger H, Dreyer T, Bausch AR, Pichlmair A, Brocker T, Zeidler R, Hammerschmidt W, Piedavent-Salomom M, López-Iglesias C, Schricker G, Haydn O, Kiechle M, Grill S, Heeren R, Knolle PA, Wilhelm O, Höchst B (2025)
Two-dimensional analysis of plasma-derived extracellular vesicles to determine the HER2 status in breast cancer patients.
Breast cancer research : BCR, Issue 1, Vol. 27, 107
DOI: 10.1186/s13058-025-02056-z, PubMed: 40524202

Rawal S, Kolarić Ð, Bohn S, Kolb D, Pavkov-Keller T, Pritišanac I, Madl T, Desfosses A, Alderson TR (2025)
A histidine switch regulates pH-dependent filament formation by the caspase-9 CARD.
bioRxiv : the preprint server for biology
DOI: 10.1101/2025.06.02.657148, PubMed: 40501686

Du Y, Lv X, Siebenmorgen T, Popowicz G, Feng C, Ma Y, Wang Y (2025)
Enhancing Catalytic Activity of a Baeyer-Villiger monooxygenase from Oceanicola granulosus: Simultaneous Engineering of the Distal Site and Active Site.
Journal of agricultural and food chemistry, Issue 23, Vol. 73, 14453-14466
DOI: 10.1021/acs.jafc.5c01791, PubMed: 40448641

Wang Z, Cao G, Collier MP, Qiu X, Broadway-Stringer S, Šaman D, Ng JZY, Sen N, Azad AJ, Hooper C, Zimmermann J, McDonough MA, Brem J, Rabe P, Song H, Alderson TR, Schofield CJ, Bolla JR, Djinovic-Carugo K, Fürst DO, Warscheid B, Degiacomi MT, Allison TM, Hochberg GKA, Robinson CV, Gehmlich K, Benesch JLP (2025)
Filamin C dimerisation is regulated by HSPB7.
Nature communications, Issue 1, Vol. 16, 4090
DOI: 10.1038/s41467-025-58889-x, PubMed: 40312381

Walla B, Maslakova A, Bischoff D, Janowski R, Niessing D, Weuster-Botz D (2025)
Rational Introduction of Electrostatic Interactions at Crystal Contacts to Enhance Protein Crystallization of an Ene Reductase.
Biomolecules, Issue 4, Vol. 15
DOI: 10.3390/biom15040467, PubMed: 40305164

Zhou J, Ridderbeek K, Zou P, Naden AB, Gaussmann S, Song F, Falter-Braun P, Kay ER, Sattler M, Cui J (2025)
Modular Nanoparticle Platform for Solution-Phase Optical Sensing of Protein-Protein Interactions.
ACS applied optical materials, Issue 3, Vol. 3, 676-688
DOI: 10.1021/acsaom.4c00486, PubMed: 40176919

Shekhar A, Di Lucrezia R, Jerye K, Korotkov VS, Harmrolfs K, Rox K, Weich HA, Ghai I, Delhommel F, Becher I, Degenhart C, Fansa E, Unger A, Habenberger P, Klebl B, Lukat P, Schmelz S, Henke S, Borgert S, Lang JC, Sasse F, Diestel R, Richter C, Schneider-Daum N, Hinkelmann B, Niemz J, Lehr CM, Jänsch L, Huehn J, Alm R, Savitski M, Welte T, Hesterkamp T, Sattler M, Winterhalter M, Blankenfeldt W, Medina E, Bilitewski U, Dinkel K, Brönstrup M (2025)
Highly potent quinoxalinediones inhibit α-hemolysin and ameliorate Staphylococcus aureus lung infections.
Cell host & microbe, Issue 4, Vol. 33, 560-572.e21
DOI: 10.1016/j.chom.2025.03.006, PubMed: 40168998

Krüger FP, Östman J, Mervin L, Tetko IV, Engkvist O (2025)
Publishing neural networks in drug discovery might compromise training data privacy.
Journal of cheminformatics, Issue 1, Vol. 17, 38
DOI: 10.1186/s13321-025-00982-w, PubMed: 40140934

Kaeuferle T, Zwermann M, Stoll N, Ferrada-Ernst P, Jablonowski L, Zeidler R, Willier S, Stenger D, Yassin A, Stripecke R, Feuchtinger T (2025)
All-in-one CRISPR/Cas-engineered glucocorticoid-receptor knock-out EBV-gp350-CAR knock-in T cells are potent and resistant to dexamethasone.
Experimental hematology & oncology, Issue 1, Vol. 14, 40
DOI: 10.1186/s40164-025-00631-w, PubMed: 40108708

Mousa N, Varbanov HP, Kaipanchery V, Gabano E, Ravera M, Toropov AA, Charochkina L, Menezes F, Godin G, Tetko IV (2025)
Online OCHEM multi-task model for solubility and lipophilicity prediction of platinum complexes.
Journal of inorganic biochemistry, Vol. 269, 112890
DOI: 10.1016/j.jinorgbio.2025.112890, PubMed: 40101341

Oberheide A, van den Oetelaar MCM, Scheele JJA, Borggräfe J, Engelen SFH, Sattler M, Ottmann C, Cossar PJ, Brunsveld L (2025)
Site-specific molecular glues for the 14-3-3/Tau pS214 protein-protein interaction via reversible covalent imine tethering.
RSC medicinal chemistry, Issue 5, Vol. 16, 2190-2201
DOI: 10.1039/d4md00833b, PubMed: 40070456

Torren-Peraire P, Verhoeven J, Herman D, Ceulemans H, Tetko IV, Wegner JK (2025)
Improving route development using convergent retrosynthesis planning.
Journal of cheminformatics, Issue 1, Vol. 17, 26
DOI: 10.1186/s13321-025-00953-1, PubMed: 40016850

Hartog PBR, Westerlund AM, Tetko IV, Genheden S (2025)
Investigations into the Efficiency of Computer-Aided Synthesis Planning.
Journal of chemical information and modeling, Issue 4, Vol. 65, 1771-1781
DOI: 10.1021/acs.jcim.4c01821, PubMed: 39889203

Lenzen B, Rösch F, Legen J, Ruwe H, Kachariya N, Sattler M, Small I, Schmitz-Linneweber C (2025)
The chloroplast RNA-binding protein CP29A supports rbcL expression during cold acclimation.
Proceedings of the National Academy of Sciences of the United States of America, Issue 5, Vol. 122, e2403969122
DOI: 10.1073/pnas.2403969122, PubMed: 39879235

Luo J, Molbay M, Chen Y, Horvath I, Kadletz K, Kick B, Zhao S, Al-Maskari R, Singh I, Ali M, Bhatia HS, Minde DP, Negwer M, Hoeher L, Calandra GM, Groschup B, Su J, Kimna C, Rong Z, Galensowske N, Todorov MI, Jeridi D, Ohn TL, Roth S, Simats A, Singh V, Khalin I, Pan C, Arús BA, Bruns OT, Zeidler R, Liesz A, Protzer U, Plesnila N, Ussar S, Hellal F, Paetzold J, Elsner M, Dietz H, Erturk A (2025)
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning.
Nature biotechnology
DOI: 10.1038/s41587-024-02528-1, PubMed: 39809933

Van Herck J, Gil MV, Jablonka KM, Abrudan A, Anker AS, Asgari M, Blaiszik B, Buffo A, Choudhury L, Corminboeuf C, Daglar H, Elahi AM, Foster IT, Garcia S, Garvin M, Godin G, Good LL, Gu J, Xiao Hu N, Jin X, Junkers T, Keskin S, Knowles TPJ, Laplaza R, Lessona M, Majumdar S, Mashhadimoslem H, McIntosh RD, Moosavi SM, Mouriño B, Nerli F, Pevida C, Poudineh N, Rajabi-Kochi M, Saar KL, Hooriabad Saboor F, Sagharichiha M, Schmidt KJ, Shi J, Simone E, Svatunek D, Taddei M, Tetko I, Tolnai D, Vahdatifar S, Whitmer J, Wieland DCF, Willumeit-Römer R, Züttel A, Smit B (2025)
Assessment of fine-tuned large language models for real-world chemistry and material science applications.
Chemical science, Issue 2, Vol. 16, 670-684
DOI: 10.1039/d4sc04401k, PubMed: 39664810

Han Z, Xia Z, Xia J, Tetko IV, Wu S (2025)
The state-of-the-art machine learning model for plasma protein binding prediction: Computational modeling with OCHEM and experimental validation.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Vol. 204, 106946
DOI: 10.1016/j.ejps.2024.106946, PubMed: 39490636

Kogut-Günthel MM, Zara Z, Nicoli A, Steuer A, Lopez-Balastegui M, Selent J, Karanth S, Koehler M, Ciancetta A, Abiko LA, Hagn F, Di Pizio A (2025)
The path to the G protein-coupled receptor structural landscape: Major milestones and future directions.
British journal of pharmacology, Issue 14, Vol. 182, 3225-3248
DOI: 10.1111/bph.17314, PubMed: 39209310