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Fully Human Herpesvirus-Specific Neutralizing IgG Antibodies Generated by EBV Immortalization of Splenocytes-Derived from Immunized Humanized Mice.
Cells, Issue 1, Vol. 13
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Talin and kindlin use integrin tail allostery and direct binding to activate integrins.
Nature structural & molecular biology, Issue 12, Vol. 30, 1913-1924
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Proceedings of the National Academy of Sciences of the United States of America, Issue 51, Vol. 120, e2310944120
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SAP30BP interacts with RBM17/SPF45 to promote splicing in a subset of human short introns.
Cell reports, Issue 12, Vol. 42, 113534
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Kinetic FRET Assay to Measure Binding-Induced Conformational Changes of Nucleic Acids.
ACS sensors, Issue 12, Vol. 8, 4597-4606
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Discovery of Inhibitory Fragments That Selectively Target Spire2-FMN2 Interaction.
Journal of medicinal chemistry, Issue 23, Vol. 66, 15715-15727
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SARS-CoV-2 and Epstein-Barr Virus-like Particles Associate and Fuse with Extracellular Vesicles in Virus Neutralization Tests.
Biomedicines, Issue 11, Vol. 11
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Integrated chemical and genetic screens unveil FSP1 mechanisms of ferroptosis regulation.
Nature structural & molecular biology, Issue 11, Vol. 30, 1806-1815
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Performance of the cross-polarization experiment in conditions of radiofrequency field inhomogeneity and slow to ultrafast magic angle spinning (MAS).
Magnetic resonance (Gottingen, Germany), Issue 2, Vol. 4, 199-215
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Systematic identification of conditionally folded intrinsically disordered regions by AlphaFold2.
Proceedings of the National Academy of Sciences of the United States of America, Issue 44, Vol. 120, e2304302120
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Binding mechanism and biological effects of flavone DYRK1A inhibitors for the design of new antidiabetics.
Scientific reports, Issue 1, Vol. 13, 18114
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Assembly-dependent Structure Formation Shapes Human Interleukin-23 versus Interleukin-12 Secretion.
Journal of molecular biology, Issue 23, Vol. 435, 168300
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Therapeutic Potential of Targeting Prokineticin Receptors in Diseases.
Pharmacological reviews, Issue 6, Vol. 75, 1167-1199
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First clinical experience with fractionated intracavitary radioimmunotherapy using [177Lu]Lu-6A10-Fab fragments in patients with glioblastoma: a pilot study.
EJNMMI research, Issue 1, Vol. 13, 78
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Menezes F, Popowicz GM (2023)
When catchers meet - a computational study on the dimerization of the Buckycatcher.
Physical chemistry chemical physics : PCCP, Issue 35, Vol. 25, 24031-24041
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5'-Ectonucleotidase CD73/NT5E supports EGFR-mediated invasion of HPV-negative head and neck carcinoma cells.
Journal of biomedical science, Issue 1, Vol. 30, 72
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Introduction to the Special Issue: AI Meets Toxicology.
Chemical research in toxicology, Issue 8, Vol. 36, 1163-1167
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Pharmacological perturbation of the phase-separating protein SMNDC1.
Nature communications, Issue 1, Vol. 14, 4504
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FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns.
Molecular cell, Issue 15, Vol. 83, 2653-2672.e15
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Troisi R, Napolitano V, Rossitto E, Osman W, Nagano M, Wakui K, Popowicz GM, Yoshimoto K, Sica F (2023)
Steric hindrance and structural flexibility shape the functional properties of a guanine-rich oligonucleotide.
Nucleic acids research, Issue 16, Vol. 51, 8880-8890
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Structural basis for specific RNA recognition by the alternative splicing factor RBM5.
Nature communications, Issue 1, Vol. 14, 4233
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MEDIATE - Molecular DockIng at homE: Turning collaborative simulations into therapeutic solutions.
Expert opinion on drug discovery, Issue 8, Vol. 18, 821-833
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Development of novel PEX5-PEX14 protein-protein interaction (PPI) inhibitors based on an oxopiperazine template.
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Nucleic acids research, Issue 16, Vol. 51, 8691-8710
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Phase separation of FSP1 promotes ferroptosis.
Nature, Issue 7969, Vol. 619, 371-377
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Mechanistic insights into the aggregation pathway of the patient-derived immunoglobulin light chain variable domain protein FOR005.
Nature communications, Issue 1, Vol. 14, 3755
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Molecular Dynamics Simulations with Grand-Canonical Reweighting Suggest Cooperativity Effects in RNA Structure Probing Experiments.
Journal of chemical theory and computation, Issue 12, Vol. 19, 3672-3685
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Structural basis of metabolite transport by the chloroplast outer envelope channel OEP21.
Nature structural & molecular biology, Issue 6, Vol. 30, 761-769
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NMR sample optimization and backbone assignment of a stabilized neurotensin receptor.
Journal of structural biology, Issue 2, Vol. 215, 107970
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Extrinsic stabilization of antiviral ACE2-Fc fusion proteins targeting SARS-CoV-2.
Communications biology, Issue 1, Vol. 6, 386
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A Buckycatcher in Solution-A Computational Perspective.
Molecules (Basel, Switzerland), Issue 6, Vol. 28
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Modernizing persistence-bioaccumulation-toxicity (PBT) assessment with high throughput animal-free methods.
Archives of toxicology, Issue 5, Vol. 97, 1267-1283
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Silmitasertib (CX-4945), a Clinically Used CK2-Kinase Inhibitor with Additional Effects on GSK3β and DYRK1A Kinases: A Structural Perspective.
Journal of medicinal chemistry, Issue 6, Vol. 66, 4009-4024
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Development of an aptamer-based screening for identification and characterization of novel RNA therapeutics using switchSENSE® technology.
Biophysical journal, Issue 3S1, Vol. 122, 357a
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Deciphering the RRM-RNA recognition code: A computational analysis.
PLoS computational biology, Issue 1, Vol. 19, e1010859
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Liquid-liquid phase separation of amyloid-β oligomers modulates amyloid fibrils formation.
The Journal of biological chemistry, Issue 3, Vol. 299, 102926
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Identification of Autophagy as a Functional Target Suitable for the Pharmacological Treatment of Mitochondrial Membrane Protein-Associated Neurodegeneration (MPAN) In Vitro.
Pharmaceutics, Issue 1, Vol. 15
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Depletion of the RNA-binding protein PURA triggers changes in posttranscriptional gene regulation and loss of P-bodies.
Nucleic acids research, Issue 3, Vol. 51, 1297-1316
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Combining NMR, SAXS and SANS to characterize the structure and dynamics of protein complexes.
Methods in enzymology, Vol. 678, 263-297
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Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Nucleic acids research, Issue 2, Vol. 51, 831-851
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Distinct conformational and energetic features define the specific recognition of (di)aromatic peptide motifs by PEX14.
Biological chemistry, Issue 2-3, Vol. 404, 179-194
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