select by year: all years - 2024 - 2023 - 2022 - 2021 - 2020 - 2019 - 2018 - 2017 - 2016 - 2015 - 2014 - 2013 - 2012 - 2011 - 2010 - 2009 - 2008 - 2007 - 2006 - 2005 - 2004 - 2003 - 2002 - 1997

select by group: all groups - Sattler - Tetko - Niessing - Reif - Hagn - Zeidler - Popowicz - Alderson

Mourão A, Bonnal S, Soni K, Warner L, Bordonné R, Valcárcel J, Sattler M (2016)
Structural basis for the recognition of spliceosomal SmN/B/B' proteins by the RBM5 OCRE domain in splicing regulation.
eLife, Vol. 5
DOI: 10.7554/eLife.14707, PubMed: 27894420

Voith von Voithenberg L, Sánchez-Rico C, Kang HS, Madl T, Zanier K, Barth A, Warner LR, Sattler M, Lamb DC (2016)
Recognition of the 3' splice site RNA by the U2AF heterodimer involves a dynamic population shift.
Proceedings of the National Academy of Sciences of the United States of America, Issue 46, Vol. 113, E7169-E7175
DOI: 10.1073/pnas.1605873113, PubMed: 27799531

Jagtap PK, Garg D, Kapp TG, Will CL, Demmer O, Lührmann R, Kessler H, Sattler M (2016)
Rational Design of Cyclic Peptide Inhibitors of U2AF Homology Motif (UHM) Domains To Modulate Pre-mRNA Splicing.
Journal of medicinal chemistry, Issue 22, Vol. 59, 10190-10197
DOI: 10.1021/acs.jmedchem.6b01118, PubMed: 27753493

Zierer BK, Rübbelke M, Tippel F, Madl T, Schopf FH, Rutz DA, Richter K, Sattler M, Buchner J (2016)
Importance of cycle timing for the function of the molecular chaperone Hsp90.
Nature structural & molecular biology, Issue 11, Vol. 23, 1020-1028
DOI: 10.1038/nsmb.3305, PubMed: 27723736

Janowski R, Scanu S, Niessing D, Madl T (2016)
Crystal and solution structural studies of mouse phospholipid hydroperoxide glutathione peroxidase 4.
Acta crystallographica. Section F, Structural biology communications, Issue Pt 10, Vol. 72, 743-749
DOI: 10.1107/S2053230X16013686, PubMed: 27710939

Subramaniam S, Erler A, Fu J, Kranz A, Tang J, Gopalswamy M, Ramakrishnan S, Keller A, Grundmeier G, Müller D, Sattler M, Stewart AF (2016)
DNA annealing by Redβ is insufficient for homologous recombination and the additional requirements involve intra- and inter-molecular interactions.
Scientific reports, Vol. 6, 34525
DOI: 10.1038/srep34525, PubMed: 27708411

Corvino A, Severino B, Fiorino F, Frecentese F, Magli E, Perissutti E, Santagada V, Bucci M, Cirino G, Kelly G, Servillo L, Popowicz G, Pastore A, Caliendo G (2016)
Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production.
Scientific reports, Vol. 6, 34398
DOI: 10.1038/srep34398, PubMed: 27708394

Delaforge E, Milles S, Huang JR, Bouvier D, Jensen MR, Sattler M, Hart DJ, Blackledge M (2016)
Investigating the Role of Large-Scale Domain Dynamics in Protein-Protein Interactions.
Frontiers in molecular biosciences, Vol. 3, 54
DOI: 10.3389/fmolb.2016.00054, PubMed: 27679800

Tetko IV, Engkvist O, Chen H (2016)
Does 'Big Data' exist in medicinal chemistry, and if so, how can it be harnessed?
Future medicinal chemistry, Issue 15, Vol. 8, 1801-1806
DOI: 10.4155/fmc-2016-0163, PubMed: 27627830

Dallmann A, Beribisky AV, Gnerlich F, Rübbelke M, Schiesser S, Carell T, Sattler M (2016)
Site-Specific Isotope-Labeling of Inosine Phosphoramidites and NMR Analysis of an Inosine-Containing RNA Duplex.
Chemistry (Weinheim an der Bergstrasse, Germany), Issue 43, Vol. 22, 15350-15359
DOI: 10.1002/chem.201602784, PubMed: 27608298

Tetko IV, Engkvist O, Koch U, Reymond JL, Chen H (2016)
BIGCHEM: Challenges and Opportunities for Big Data Analysis in Chemistry.
Molecular informatics, Issue 11-12, Vol. 35, 615-621
DOI: 10.1002/minf.201600073, PubMed: 27464907

Guo S, Popowicz GM, Li D, Yuan D, Wang Y (2016)
Lid mobility in lipase SMG1 validated using a thiol/disulfide redox potential probe.
FEBS open bio, Issue 5, Vol. 6, 477-83
DOI: 10.1002/2211-5463.12059, PubMed: 27419053

Guaitoli G, Raimondi F, Gilsbach BK, Gómez-Llorente Y, Deyaert E, Renzi F, Li X, Schaffner A, Jagtap PK, Boldt K, von Zweydorf F, Gotthardt K, Lorimer DD, Yue Z, Burgin A, Janjic N, Sattler M, Versées W, Ueffing M, Ubarretxena-Belandia I, Kortholt A, Gloeckner CJ (2016)
Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.
Proceedings of the National Academy of Sciences of the United States of America, Issue 30, Vol. 113, E4357-66
DOI: 10.1073/pnas.1523708113, PubMed: 27357661

Zheng X, Ramani A, Soni K, Gottardo M, Zheng S, Ming Gooi L, Li W, Feng S, Mariappan A, Wason A, Widlund P, Pozniakovsky A, Poser I, Deng H, Ou G, Riparbelli M, Giuliano C, Hyman AA, Sattler M, Gopalakrishnan J, Li H (2016)
Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length.
Nature communications, Vol. 7, 11874
DOI: 10.1038/ncomms11874, PubMed: 27306797

Goricanec D, Stehle R, Egloff P, Grigoriu S, Plückthun A, Wagner G, Hagn F (2016)
Conformational dynamics of a G-protein α subunit is tightly regulated by nucleotide binding.
Proceedings of the National Academy of Sciences of the United States of America, Issue 26, Vol. 113, E3629-38
DOI: 10.1073/pnas.1604125113, PubMed: 27298341

Baskin II, Winkler D, Tetko IV (2016)
A renaissance of neural networks in drug discovery.
Expert opinion on drug discovery, Issue 8, Vol. 11, 785-95
DOI: 10.1080/17460441.2016.1201262, PubMed: 27295548

Enthart A, Klein C, Dehner A, Coles M, Gemmecker G, Kessler H, Hagn F (2016)
Solution structure and binding specificity of the p63 DNA binding domain.
Scientific reports, Vol. 6, 26707
DOI: 10.1038/srep26707, PubMed: 27225672

Novotarskyi S, Abdelaziz A, Sushko Y, Körner R, Vogt J, Tetko IV (2016)
ToxCast EPA in Vitro to in Vivo Challenge: Insight into the Rank-I Model.
Chemical research in toxicology, Issue 5, Vol. 29, 768-75
DOI: 10.1021/acs.chemrestox.5b00481, PubMed: 27120770

Brenke JK, Salmina ES, Ringelstetter L, Dornauer S, Kuzikov M, Rothenaigner I, Schorpp K, Giehler F, Gopalakrishnan J, Kieser A, Gul S, Tetko IV, Hadian K (2016)
Identification of Small-Molecule Frequent Hitters of Glutathione S-Transferase-Glutathione Interaction.
Journal of biomolecular screening, Issue 6, Vol. 21, 596-607
DOI: 10.1177/1087057116639992, PubMed: 27044684

Sarkar R, Mainz A, Busi B, Barbet-Massin E, Kranz M, Hofmann T, Reif B (2016)
Immobilization of soluble protein complexes in MAS solid-state NMR: Sedimentation versus viscosity.
Solid state nuclear magnetic resonance, Vol. 76-77, 7-14
DOI: 10.1016/j.ssnmr.2016.03.005, PubMed: 27017576

Janowski R, Heinz GA, Schlundt A, Wommelsdorf N, Brenner S, Gruber AR, Blank M, Buch T, Buhmann R, Zavolan M, Niessing D, Heissmeyer V, Sattler M (2016)
Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40.
Nature communications, Vol. 7, 11032
DOI: 10.1038/ncomms11032, PubMed: 27010430

Jung B, Messias AC, Schorpp K, Geerlof A, Schneider G, Saur D, Hadian K, Sattler M, Wanker EE, Hasenöder S, Lickert H (2016)
Novel small molecules targeting ciliary transport of Smoothened and oncogenic Hedgehog pathway activation.
Scientific reports, Vol. 6, 22540
DOI: 10.1038/srep22540, PubMed: 26931153

Mansouri K, Abdelaziz A, Rybacka A, Roncaglioni A, Tropsha A, Varnek A, Zakharov A, Worth A, Richard AM, Grulke CM, Trisciuzzi D, Fourches D, Horvath D, Benfenati E, Muratov E, Wedebye EB, Grisoni F, Mangiatordi GF, Incisivo GM, Hong H, Ng HW, Tetko IV, Balabin I, Kancherla J, Shen J, Burton J, Nicklaus M, Cassotti M, Nikolov NG, Nicolotti O, Andersson PL, Zang Q, Politi R, Beger RD, Todeschini R, Huang R, Farag S, Rosenberg SA, Slavov S, Hu X, Judson RS (2016)
CERAPP: Collaborative Estrogen Receptor Activity Prediction Project.
Environmental health perspectives, Issue 7, Vol. 124, 1023-33
DOI: 10.1289/ehp.1510267, PubMed: 26908244

Jung B, Padula D, Burtscher I, Landerer C, Lutter D, Theis F, Messias AC, Geerlof A, Sattler M, Kremmer E, Boldt K, Ueffing M, Lickert H (2016)
Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation.
PloS one, Issue 2, Vol. 11, e0149477
DOI: 10.1371/journal.pone.0149477, PubMed: 26901434

Prade E, Barucker C, Sarkar R, Althoff-Ospelt G, Lopez del Amo JM, Hossain S, Zhong Y, Multhaup G, Reif B (2016)
Sulindac Sulfide Induces the Formation of Large Oligomeric Aggregates of the Alzheimer's Disease Amyloid-β Peptide Which Exhibit Reduced Neurotoxicity.
Biochemistry, Issue 12, Vol. 55, 1839-49
DOI: 10.1021/acs.biochem.5b01272, PubMed: 26900939

Schlundt A, Niessing D, Heissmeyer V, Sattler M (2016)
RNA recognition by Roquin in posttranscriptional gene regulation.
Wiley interdisciplinary reviews. RNA, Issue 4, Vol. 7, 455-69
DOI: 10.1002/wrna.1333, PubMed: 26844532

Nokwe CN, Hora M, Zacharias M, Yagi H, Peschek J, Reif B, Goto Y, Buchner J (2016)
A Stable Mutant Predisposes Antibody Domains to Amyloid Formation through Specific Non-Native Interactions.
Journal of molecular biology, Issue 6, Vol. 428, 1315-1332
DOI: 10.1016/j.jmb.2016.01.015, PubMed: 26827727

Alderson TR, Bax A (2016)
Parkinson's disease: Disorder in the court.
Nature, Issue 7588, Vol. 530, 38-9
DOI: 10.1038/nature16871, PubMed: 26808901

Tetko IV, M Lowe D, Williams AJ (2016)
The development of models to predict melting and pyrolysis point data associated with several hundred thousand compounds mined from PATENTS.
Journal of cheminformatics, Vol. 8, 2
DOI: 10.1186/s13321-016-0113-y, PubMed: 26807157

Carlon A, Ravera E, Hennig J, Parigi G, Sattler M, Luchinat C (2016)
Improved Accuracy from Joint X-ray and NMR Refinement of a Protein-RNA Complex Structure.
Journal of the American Chemical Society, Issue 5, Vol. 138, 1601-10
DOI: 10.1021/jacs.5b11598, PubMed: 26761154

Feracci M, Foot JN, Grellscheid SN, Danilenko M, Stehle R, Gonchar O, Kang HS, Dalgliesh C, Meyer NH, Liu Y, Lahat A, Sattler M, Eperon IC, Elliott DJ, Dominguez C (2016)
Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
Nature communications, Vol. 7, 10355
DOI: 10.1038/ncomms10355, PubMed: 26758068

Golestanian S, Sharifi A, Popowicz GM, Azizian H, Foroumadi A, Szwagierczak A, Holak TA, Amanlou M (2016)
Discovery of novel dual inhibitors against Mdm2 and Mdmx proteins by in silico approaches and binding assay.
Life sciences, Vol. 145, 240-6
DOI: 10.1016/j.lfs.2015.12.047, PubMed: 26746660

Weber J, Bao H, Hartlmüller C, Wang Z, Windhager A, Janowski R, Madl T, Jin P, Niessing D (2016)
Structural basis of nucleic-acid recognition and double-strand unwinding by the essential neuronal protein Pur-alpha.
eLife, Vol. 5
DOI: 10.7554/eLife.11297, PubMed: 26744780

Vincendeau M, Hadian K, Messias AC, Brenke JK, Halander J, Griesbach R, Greczmiel U, Bertossi A, Stehle R, Nagel D, Demski K, Velvarska H, Niessing D, Geerlof A, Sattler M, Krappmann D (2016)
Inhibition of Canonical NF-κB Signaling by a Small Molecule Targeting NEMO-Ubiquitin Interaction.
Scientific reports, Vol. 6, 18934
DOI: 10.1038/srep18934, PubMed: 26740240

Tetko IV, Varbanov HP, Galanski MS, Talmaciu M, Platts JA, Ravera M, Gabano E (2016)
Prediction of logP for Pt(II) and Pt(IV) complexes: Comparison of statistical and quantum-chemistry based approaches.
Journal of inorganic biochemistry, Vol. 156, 1-13
DOI: 10.1016/j.jinorgbio.2015.12.006, PubMed: 26717258

Morgen M, Jöst C, Malz M, Janowski R, Niessing D, Klein CD, Gunkel N, Miller AK (2016)
Spiroepoxytriazoles Are Fumagillin-like Irreversible Inhibitors of MetAP2 with Potent Cellular Activity.
ACS chemical biology, Issue 4, Vol. 11, 1001-11
DOI: 10.1021/acschembio.5b00755, PubMed: 26686773

Emmanouilidis L, Gopalswamy M, Passon DM, Wilmanns M, Sattler M (2016)
Structural biology of the import pathways of peroxisomal matrix proteins.
Biochimica et biophysica acta, Issue 5, Vol. 1863, 804-13
DOI: 10.1016/j.bbamcr.2015.09.034, PubMed: 26450166

Giannopoulou EA, Emmanouilidis L, Sattler M, Dodt G, Wilmanns M (2016)
Towards the molecular mechanism of the integration of peroxisomal membrane proteins.
Biochimica et biophysica acta, Issue 5, Vol. 1863, 863-9
DOI: 10.1016/j.bbamcr.2015.09.031, PubMed: 26434995