Calonaci N, Jones A, Cuturello F, Sattler M, Bussi G (2020) Machine learning a model for RNA structure prediction. NAR genomics and bioinformatics, Issue 4, Vol. 2, lqaa090 DOI: 10.1093/nargab/lqaa090, PubMed: 33575634 |
Jagtap PKA, Kubelka T, Soni K, Will CL, Garg D, Sippel C, Kapp TG, Potukuchi HK, Schorpp K, Hadian K, Kessler H, Lührmann R, Hausch F, Bach T, Sattler M (2020) Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly. Nature communications, Issue 1, Vol. 11, 5621 DOI: 10.1038/s41467-020-19514-1, PubMed: 33159082 |
Donau C, Späth F, Sosson M, Kriebisch BAK, Schnitter F, Tena-Solsona M, Kang HS, Salibi E, Sattler M, Mutschler H, Boekhoven J (2020) Active coacervate droplets as a model for membraneless organelles and protocells. Nature communications, Issue 1, Vol. 11, 5167 DOI: 10.1038/s41467-020-18815-9, PubMed: 33056997 |
Jussupow A, Messias AC, Stehle R, Geerlof A, Solbak SMØ, Paissoni C, Bach A, Sattler M, Camilloni C (2020) The dynamics of linear polyubiquitin. Science advances, Issue 42, Vol. 6 DOI: 10.1126/sciadv.abc3786, PubMed: 33055165 |
Santovito D, Egea V, Bidzhekov K, Natarelli L, Mourão A, Blanchet X, Wichapong K, Aslani M, Brunßen C, Horckmans M, Hristov M, Geerlof A, Lutgens E, Daemen MJAP, Hackeng T, Ries C, Chavakis T, Morawietz H, Naumann R, Hundelshausen PV, Steffens S, Duchêne J, Megens RTA, Sattler M, Weber C (2020) Autophagy unleashes noncanonical microRNA functions. Autophagy, Issue 12, Vol. 16, 2294-2296 DOI: 10.1080/15548627.2020.1830523, PubMed: 33054575 |
Reinking HK, Kang HS, Götz MJ, Li HY, Kieser A, Zhao S, Acampora AC, Weickert P, Fessler E, Jae LT, Sattler M, Stingele J (2020) DNA Structure-Specific Cleavage of DNA-Protein Crosslinks by the SPRTN Protease. Molecular cell, Issue 1, Vol. 80, 102-113.e6 DOI: 10.1016/j.molcel.2020.08.003, PubMed: 32853547 |
Delhommel F, Sattler M (2020) When Less Is More: Combining Site-Specific Isotope Labeling and NMR Unravels Structural Details of Huntingtin Repeats. Structure (London, England : 1993), Issue 7, Vol. 28, 730-732 DOI: 10.1016/j.str.2020.06.005, PubMed: 32640252 |
Softley CA, Zak KM, Bostock MJ, Fino R, Zhou RX, Kolonko M, Mejdi-Nitiu R, Meyer H, Sattler M, Popowicz GM (2020) Correction for Softley et al., "Structure and Molecular Recognition Mechanism of IMP-13 Metallo-β-Lactamase". Antimicrobial agents and chemotherapy, Issue 7, Vol. 64 DOI: 10.1128/AAC.01077-20, PubMed: 32576598 |
Softley CA, Bostock MJ, Popowicz GM, Sattler M (2020) Paramagnetic NMR in drug discovery. Journal of biomolecular NMR, Issue 6-7, Vol. 74, 287-309 DOI: 10.1007/s10858-020-00322-0, PubMed: 32524233 |
Santovito D, Egea V, Bidzhekov K, Natarelli L, Mourão A, Blanchet X, Wichapong K, Aslani M, Brunßen C, Horckmans M, Hristov M, Geerlof A, Lutgens E, Daemen MJAP, Hackeng T, Ries C, Chavakis T, Morawietz H, Naumann R, von Hundelshausen P, Steffens S, Duchêne J, Megens RTA, Sattler M, Weber C (2020) Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosis. Science translational medicine, Issue 546, Vol. 12 DOI: 10.1126/scitranslmed.aaz2294, PubMed: 32493793 |
Soni K, Martínez-Lumbreras S, Sattler M (2020) Conformational Dynamics from Ambiguous Zinc Coordination in the RanBP2-Type Zinc Finger of RBM5. Journal of molecular biology, Issue 14, Vol. 432, 4127-4138 DOI: 10.1016/j.jmb.2020.05.012, PubMed: 32450081 |
Su W, Tan H, Janowski R, Zhang W, Wang P, Zhang J, Zhai H, Li J, Niessing D, Sattler M, Zou P (2020) Ferritin-Displayed GLP-1 with Improved Pharmacological Activities and Pharmacokinetics. Molecular pharmaceutics, Issue 5, Vol. 17, 1663-1673 DOI: 10.1021/acs.molpharmaceut.0c00098, PubMed: 32243177 |
Vieweg S, Mulholland K, Bräuning B, Kachariya N, Lai YC, Toth R, Singh PK, Volpi I, Sattler M, Groll M, Itzen A, Muqit MMK (2020) PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2-mediated phosphorylation at Threonine72. The Biochemical journal, Issue 9, Vol. 477, 1651-1668 DOI: 10.1042/BCJ20190664, PubMed: 32227113 |
Softley CA, Zak KM, Bostock MJ, Fino R, Zhou RX, Kolonko M, Mejdi-Nitiu R, Meyer H, Sattler M, Popowicz GM (2020) Structure and Molecular Recognition Mechanism of IMP-13 Metallo-β-Lactamase. Antimicrobial agents and chemotherapy, Issue 6, Vol. 64, e00123-20 DOI: 10.1128/AAC.00123-20, PubMed: 32205343 |
Delhommel F, Gabel F, Sattler M (2020) Current approaches for integrating solution NMR spectroscopy and small-angle scattering to study the structure and dynamics of biomolecular complexes. Journal of molecular biology, Issue 9, Vol. 432, 2890-2912 DOI: 10.1016/j.jmb.2020.03.014, PubMed: 32199983 |
Ratkova EL, Dawidowski M, Napolitano V, Dubin G, Fino R, Ostertag MS, Sattler M, Popowicz G, Tetko IV (2020) Water envelope has a critical impact on the design of protein-protein interaction inhibitors. Chemical communications (Cambridge, England), Issue 31, Vol. 56, 4360-4363 DOI: 10.1039/c9cc07714f, PubMed: 32195483 |
Kang HS, Sánchez-Rico C, Ebersberger S, Sutandy FXR, Busch A, Welte T, Stehle R, Hipp C, Schulz L, Buchbender A, Zarnack K, König J, Sattler M (2020) An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2. Proceedings of the National Academy of Sciences of the United States of America, Issue 13, Vol. 117, 7140-7149 DOI: 10.1073/pnas.1913483117, PubMed: 32188783 |
Mader SL, Lopez A, Lawatscheck J, Luo Q, Rutz DA, Gamiz-Hernandez AP, Sattler M, Buchner J, Kaila VRI (2020) Conformational dynamics modulate the catalytic activity of the molecular chaperone Hsp90. Nature communications, Issue 1, Vol. 11, 1410 DOI: 10.1038/s41467-020-15050-0, PubMed: 32179743 |
De Angelis M, Schriever SC, Kyriakou E, Sattler M, Messias AC, Schramm KW, Pfluger PT (2020) Detection and quantification of the anti-obesity drug celastrol in murine liver and brain. Neurochemistry international, Vol. 136, 104713 DOI: 10.1016/j.neuint.2020.104713, PubMed: 32151623 |
Barthelmes K, Ramcke E, Kang HS, Sattler M, Itzen A (2020) Conformational control of small GTPases by AMPylation. Proceedings of the National Academy of Sciences of the United States of America, Issue 11, Vol. 117, 5772-5781 DOI: 10.1073/pnas.1917549117, PubMed: 32123090 |
Denis M, Softley C, Giuntini S, Gentili M, Ravera E, Parigi G, Fragai M, Popowicz G, Sattler M, Luchinat C, Cerofolini L, Nativi C (2020) The Photocatalyzed Thiol-ene reaction: A New Tag to Yield Fast, Selective and reversible Paramagnetic Tagging of Proteins. Chemphyschem : a European journal of chemical physics and physical chemistry, Issue 9, Vol. 21, 863-869 DOI: 10.1002/cphc.202000071, PubMed: 32092218 |
Göttlicher M, Sattler M, Brönstrup M (2020) New Frontiers in Drug Discovery: Academia Meets Industry at the International Helmholtz Drug Discovery Conference (HDDC). ChemMedChem, Issue 5, Vol. 15, 468-470 DOI: 10.1002/cmdc.202000019, PubMed: 32080972 |
Solbak SMØ, Zang J, Narayanan D, Høj LJ, Bucciarelli S, Softley C, Meier S, Langkilde AE, Gotfredsen CH, Sattler M, Bach A (2020) Developing Inhibitors of the p47phox-p22phox Protein-Protein Interaction by Fragment-Based Drug Discovery. Journal of medicinal chemistry, Issue 3, Vol. 63, 1156-1177 DOI: 10.1021/acs.jmedchem.9b01492, PubMed: 31922756 |
Niu Z, Prade E, Malideli E, Hille K, Jussupow A, Mideksa YG, Yan LM, Qian C, Fleisch M, Messias AC, Sarkar R, Sattler M, Lamb DC, Feige MJ, Camilloni C, Kapurniotu A, Reif B (2020) Structural Insight into IAPP-Derived Amyloid Inhibitors and Their Mechanism of Action. Angewandte Chemie (International ed. in English), Issue 14, Vol. 59, 5771-5781 DOI: 10.1002/anie.201914559, PubMed: 31863711 |
Dawidowski M, Kalel VC, Napolitano V, Fino R, Schorpp K, Emmanouilidis L, Lenhart D, Ostertag M, Kaiser M, Kolonko M, Tippler B, Schliebs W, Dubin G, Mäser P, Tetko IV, Hadian K, Plettenburg O, Erdmann R, Sattler M, Popowicz GM (2020) Structure-Activity Relationship in Pyrazolo[4,3-c]pyridines, First Inhibitors of PEX14-PEX5 Protein-Protein Interaction with Trypanocidal Activity. Journal of medicinal chemistry, Issue 2, Vol. 63, 847-879 DOI: 10.1021/acs.jmedchem.9b01876, PubMed: 31860309 |