Kang HS, Sattler M (2018) Capturing dynamic conformational shifts in protein-ligand recognition using integrative structural biology in solution. Emerging topics in life sciences, Issue 1, Vol. 2, 107-119 DOI: 10.1042/ETLS20170090, PubMed: 33525784 |
Tan H, Su W, Zhang W, Wang P, Sattler M, Zou P (2018) Recent Advances in Half-life Extension Strategies for Therapeutic Peptides and Proteins. Current pharmaceutical design, Issue 41, Vol. 24, 4932-4946 DOI: 10.2174/1381612825666190206105232, PubMed: 30727869 |
Kyriakou E, Schmidt S, Dodd GT, Pfuhlmann K, Simonds SE, Lenhart D, Geerlof A, Schriever SC, De Angelis M, Schramm KW, Plettenburg O, Cowley MA, Tiganis T, Tschöp MH, Pfluger PT, Sattler M, Messias AC (2018) Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus. Journal of medicinal chemistry, Issue 24, Vol. 61, 11144-11157 DOI: 10.1021/acs.jmedchem.8b01224, PubMed: 30525586 |
Kalel VC, Mäser P, Sattler M, Erdmann R, Popowicz GM (2018) Come, sweet death: targeting glycosomal protein import for antitrypanosomal drug development. Current opinion in microbiology, Vol. 46, 116-122 DOI: 10.1016/j.mib.2018.11.003, PubMed: 30481613 |
Essig K, Kronbeck N, Guimaraes JC, Lohs C, Schlundt A, Hoffmann A, Behrens G, Brenner S, Kowalska J, Lopez-Rodriguez C, Jemielity J, Holtmann H, Reiche K, Hackermüller J, Sattler M, Zavolan M, Heissmeyer V (2018) Roquin targets mRNAs in a 3'-UTR-specific manner by different modes of regulation. Nature communications, Issue 1, Vol. 9, 3810 DOI: 10.1038/s41467-018-06184-3, PubMed: 30232334 |
Pfuhlmann K, Schriever SC, Baumann P, Kabra DG, Harrison L, Mazibuko-Mbeje SE, Contreras RE, Kyriakou E, Simonds SE, Tiganis T, Cowley MA, Woods SC, Jastroch M, Clemmensen C, De Angelis M, Schramm KW, Sattler M, Messias AC, Tschöp MH, Pfluger PT (2018) Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1. Diabetes, Issue 11, Vol. 67, 2456-2465 DOI: 10.2337/db18-0146, PubMed: 30158241 |
Brenke JK, Popowicz GM, Schorpp K, Rothenaigner I, Roesner M, Meininger I, Kalinski C, Ringelstetter L, R'kyek O, Jürjens G, Vincendeau M, Plettenburg O, Sattler M, Krappmann D, Hadian K (2018) Targeting TRAF6 E3 ligase activity with a small-molecule inhibitor combats autoimmunity. The Journal of biological chemistry, Issue 34, Vol. 293, 13191-13203 DOI: 10.1074/jbc.RA118.002649, PubMed: 29950522 |
Kooshapur H, Choudhury NR, Simon B, Mühlbauer M, Jussupow A, Fernandez N, Jones AN, Dallmann A, Gabel F, Camilloni C, Michlewski G, Caceres JF, Sattler M (2018) Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1. Nature communications, Issue 1, Vol. 9, 2479 DOI: 10.1038/s41467-018-04871-9, PubMed: 29946118 |
Iuso A, Wiersma M, Schüller HJ, Pode-Shakked B, Marek-Yagel D, Grigat M, Schwarzmayr T, Berutti R, Alhaddad B, Kanon B, Grzeschik NA, Okun JG, Perles Z, Salem Y, Barel O, Vardi A, Rubinshtein M, Tirosh T, Dubnov-Raz G, Messias AC, Terrile C, Barshack I, Volkov A, Avivi C, Eyal E, Mastantuono E, Kumbar M, Abudi S, Braunisch M, Strom TM, Meitinger T, Hoffmann GF, Prokisch H, Haack TB, Brundel BJJM, Haas D, Sibon OCM, Anikster Y (2018) Mutations in PPCS, Encoding Phosphopantothenoylcysteine Synthetase, Cause Autosomal-Recessive Dilated Cardiomyopathy. American journal of human genetics, Issue 6, Vol. 102, 1018-1030 DOI: 10.1016/j.ajhg.2018.03.022, PubMed: 29754768 |
Ghosh D, Koch U, Hadian K, Sattler M, Tetko IV (2018) Luciferase Advisor: High-Accuracy Model To Flag False Positive Hits in Luciferase HTS Assays. Journal of chemical information and modeling, Issue 5, Vol. 58, 933-942 DOI: 10.1021/acs.jcim.7b00574, PubMed: 29667823 |
Rutz DA, Luo Q, Freiburger L, Madl T, Kaila VRI, Sattler M, Buchner J (2018) A switch point in the molecular chaperone Hsp90 responding to client interaction. Nature communications, Issue 1, Vol. 9, 1472 DOI: 10.1038/s41467-018-03946-x, PubMed: 29662162 |
Sutandy FXR, Ebersberger S, Huang L, Busch A, Bach M, Kang HS, Fallmann J, Maticzka D, Backofen R, Stadler PF, Zarnack K, Sattler M, Legewie S, König J (2018) In vitro iCLIP-based modeling uncovers how the splicing factor U2AF2 relies on regulation by cofactors. Genome research, Issue 5, Vol. 28, 699-713 DOI: 10.1101/gr.229757.117, PubMed: 29643205 |
Tomala MD, Magiera-Mularz K, Kubica K, Krzanik S, Zieba B, Musielak B, Pustula M, Popowicz GM, Sattler M, Dubin G, Skalniak L, Holak TA (2018) Identification of small-molecule inhibitors of USP2a. European journal of medicinal chemistry, Vol. 150, 261-267 DOI: 10.1016/j.ejmech.2018.03.009, PubMed: 29529503 |
Asami S, Kallies W, Günther JC, Stavropoulou M, Glaser SJ, Sattler M (2018) Ultrashort Broadband Cooperative Pulses for Multidimensional Biomolecular NMR Experiments. Angewandte Chemie (International ed. in English), Issue 44, Vol. 57, 14498-14502 DOI: 10.1002/anie.201800220, PubMed: 29508496 |
Colaluca IN, Basile A, Freiburger L, D'Uva V, Disalvatore D, Vecchi M, Confalonieri S, Tosoni D, Cecatiello V, Malabarba MG, Yang CJ, Kainosho M, Sattler M, Mapelli M, Pece S, Di Fiore PP (2018) A Numb-Mdm2 fuzzy complex reveals an isoform-specific involvement of Numb in breast cancer. The Journal of cell biology, Issue 2, Vol. 217, 745-762 DOI: 10.1083/jcb.201709092, PubMed: 29269425 |
Supekar S, Papageorgiou AC, Gemmecker G, Peltzer R, Johansson MP, Tripsianes K, Sattler M, Kaila VRI (2018) Conformational Selection of Dimethylarginine Recognition by the Survival Motor Neuron Tudor Domain. Angewandte Chemie (International ed. in English), Issue 2, Vol. 57, 486-490 DOI: 10.1002/anie.201708233, PubMed: 28980372 |