Narayanan D, Tran KT, Pallesen JS, Solbak SMØ, Qin Y, Mukminova E, Luchini M, Vasilyeva KO, González Chichón D, Goutsiou G, Poulsen C, Haapanen N, Popowicz GM, Sattler M, Olagnier D, Gajhede M, Bach A (2022)
Development of Noncovalent Small-Molecule Keap1-Nrf2 Inhibitors by Fragment-Based Drug Discovery.
Journal of medicinal chemistry, Issue 21, Vol. 65, 14481-14526
DOI: 10.1021/acs.jmedchem.2c00830, PubMed: 36263945 |
Napolitano V, Mróz P, Marciniak M, Kalel VC, Softley CA, Janna Olmos JD, Tippler BG, Schorpp K, Rioton S, Fröhlich T, Plettenburg O, Hadian K, Erdmann R, Sattler M, Popowicz GM, Dawidowski M, Dubin G (2022)
Structure-based design, synthesis and evaluation of a novel family of PEX5-PEX14 interaction inhibitors against Trypanosoma.
European journal of medicinal chemistry, Vol. 243, 114778
DOI: 10.1016/j.ejmech.2022.114778, PubMed: 36194937 |
Kitel R, Rodríguez I, Del Corte X, Atmaj J, Żarnik M, Surmiak E, Muszak D, Magiera-Mularz K, Popowicz GM, Holak TA, Musielak B (2022)
Exploring the Surface of the Ectodomain of the PD-L1 Immune Checkpoint with Small-Molecule Fragments.
ACS chemical biology, Issue 9, Vol. 17, 2655-2663
DOI: 10.1021/acschembio.2c00583, PubMed: 36073782 |
Napolitano V, Softley CA, Blat A, Kalel VC, Schorpp K, Siebenmorgen T, Hadian K, Erdmann R, Sattler M, Popowicz GM, Dubin G (2022)
Small molecule mediated inhibition of protein cargo recognition by peroxisomal transport receptor PEX5 is toxic to Trypanosoma.
Scientific reports, Issue 1, Vol. 12, 14705
DOI: 10.1038/s41598-022-18841-1, PubMed: 36038611 |
Menezes F, Popowicz GM (2022)
ULYSSES: An Efficient and Easy to Use Semiempirical Library for C+.
Journal of chemical information and modeling, Issue 16, Vol. 62, 3685-3694
DOI: 10.1021/acs.jcim.2c00757, PubMed: 35930308 |
Menezes F, Popowicz GM (2022)
Acid Rain and Flue Gas: Quantum Chemical Hydrolysis of NO2.
Chemphyschem : a European journal of chemical physics and physical chemistry, Issue 21, Vol. 23, e202200395
DOI: 10.1002/cphc.202200395, PubMed: 35875889 |
Menezes F, Popowicz GM (2022)
How to Catch the Ball: Fullerene Binding to the Corannulene Pincer.
Molecules (Basel, Switzerland), Issue 12, Vol. 27
DOI: 10.3390/molecules27123838, PubMed: 35744963 |
Jones AN, Mourão A, Czarna A, Matsuda A, Fino R, Pyrc K, Sattler M, Popowicz GM (2022)
Characterization of SARS-CoV-2 replication complex elongation and proofreading activity.
Scientific reports, Issue 1, Vol. 12, 9593
DOI: 10.1038/s41598-022-13380-1, PubMed: 35688849 |
Czarna A, Plewka J, Kresik L, Matsuda A, Karim A, Robinson C, O'Byrne S, Cunningham F, Georgiou I, Wilk P, Pachota M, Popowicz G, Wyatt PG, Dubin G, Pyrć K (2022)
Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity.
Structure (London, England : 1993), Issue 8, Vol. 30, 1050-1054.e2
DOI: 10.1016/j.str.2022.04.014, PubMed: 35609600 |
Popowicz GM, Pyrc K, Hadian K (2022)
Vaccination versus SARS-CoV-2 Omicron: three vaccine doses win the battle.
Signal transduction and targeted therapy, Issue 1, Vol. 7, 140
DOI: 10.1038/s41392-022-01000-3, PubMed: 35477929 |
Biebl MM, Delhommel F, Faust O, Zak KM, Agam G, Guo X, Mühlhofer M, Dahiya V, Hillebrand D, Popowicz GM, Kampmann M, Lamb DC, Rosenzweig R, Sattler M, Buchner J (2022)
NudC guides client transfer between the Hsp40/70 and Hsp90 chaperone systems.
Molecular cell, Issue 3, Vol. 82, 555-569.e7
DOI: 10.1016/j.molcel.2021.12.031, PubMed: 35063133 |
Napolitano V, Dabrowska A, Schorpp K, Mourão A, Barreto-Duran E, Benedyk M, Botwina P, Brandner S, Bostock M, Chykunova Y, Czarna A, Dubin G, Fröhlich T, Hölscher M, Jedrysik M, Matsuda A, Owczarek K, Pachota M, Plettenburg O, Potempa J, Rothenaigner I, Schlauderer F, Slysz K, Szczepanski A, Greve-Isdahl Mohn K, Blomberg B, Sattler M, Hadian K, Popowicz GM, Pyrc K (2022)
Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses.
Cell chemical biology, Issue 5, Vol. 29, 774-784.e8
DOI: 10.1016/j.chembiol.2021.11.006, PubMed: 35021060 |
Borchard S, Raschke S, Zak KM, Eberhagen C, Einer C, Weber E, Müller SM, Michalke B, Lichtmannegger J, Wieser A, Rieder T, Popowicz GM, Adamski J, Klingenspor M, Coles AH, Viana R, Vendelbo MH, Sandahl TD, Schwerdtle T, Plitz T, Zischka H (2022)
Bis-choline tetrathiomolybdate prevents copper-induced blood-brain barrier damage.
Life science alliance, Issue 3, Vol. 5
DOI: 10.26508/lsa.202101164, PubMed: 34857647 |
Chrustowicz J, Sherpa D, Teyra J, Loke MS, Popowicz GM, Basquin J, Sattler M, Prabu JR, Sidhu SS, Schulman BA (2022)
Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases.
Journal of molecular biology, Issue 2, Vol. 434, 167347
DOI: 10.1016/j.jmb.2021.167347, PubMed: 34767800 |
