Li M, Gaussmann S, Tippler B, Ott J, Popowicz GM, Schliebs W, Sattler M, Erdmann R, Kalel VC (2021)
Novel Trypanocidal Inhibitors that Block Glycosome Biogenesis by Targeting PEX3-PEX19 Interaction.
Frontiers in cell and developmental biology, Vol. 9, 737159
DOI: 10.3389/fcell.2021.737159, PubMed: 34988071

Olguín-Contreras LF, Mendler AN, Popowicz G, Hu B, Noessner E (2021)
Double Strike Approach for Tumor Attack: Engineering T Cells Using a CD40L:CD28 Chimeric Co-Stimulatory Switch Protein for Enhanced Tumor Targeting in Adoptive Cell Therapy.
Frontiers in immunology, Vol. 12, 750478
DOI: 10.3389/fimmu.2021.750478, PubMed: 34912334

Fino R, Lenhart D, Kalel VC, Softley CA, Napolitano V, Byrne R, Schliebs W, Dawidowski M, Erdmann R, Sattler M, Schneider G, Plettenburg O, Popowicz GM (2021)
Computer-Aided Design and Synthesis of a New Class of PEX14 Inhibitors: Substituted 2,3,4,5-Tetrahydrobenzo[F][1,4]oxazepines as Potential New Trypanocidal Agents.
Journal of chemical information and modeling, Issue 10, Vol. 61, 5256-5268
DOI: 10.1021/acs.jcim.1c00472, PubMed: 34597510

Reyes Romero A, Lunev S, Popowicz GM, Calderone V, Gentili M, Sattler M, Plewka J, Taube M, Kozak M, Holak TA, Dömling ASS, Groves MR (2021)
A fragment-based approach identifies an allosteric pocket that impacts malate dehydrogenase activity.
Communications biology, Issue 1, Vol. 4, 949
DOI: 10.1038/s42003-021-02442-1, PubMed: 34376783

Zak KM, Bostock MJ, Waligorska I, Thøgersen IB, Enghild JJ, Popowicz GM, Grudnik P, Potempa J, Ksiazek M (2021)
Latency, thermal stability, and identification of an inhibitory compound of mirolysin, a secretory protease of the human periodontopathogen Tannerella forsythia.
Journal of enzyme inhibition and medicinal chemistry, Issue 1, Vol. 36, 1267-1281
DOI: 10.1080/14756366.2021.1937619, PubMed: 34210221

Pallesen JS, Narayanan D, Tran KT, Solbak SMØ, Marseglia G, Sørensen LME, Høj LJ, Munafò F, Carmona RMC, Garcia AD, Desu HL, Brambilla R, Johansen TN, Popowicz GM, Sattler M, Gajhede M, Bach A (2021)
Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds.
Journal of medicinal chemistry, Issue 8, Vol. 64, 4623-4661
DOI: 10.1021/acs.jmedchem.0c02094, PubMed: 33818106