Kang HS, Sattler M (2018)
Capturing dynamic conformational shifts in protein-ligand recognition using integrative structural biology in solution.
Emerging topics in life sciences, Issue 1, Vol. 2, 107-119
DOI: 10.1042/ETLS20170090, PubMed: 33525784

Tan H, Su W, Zhang W, Wang P, Sattler M, Zou P (2018)
Recent Advances in Half-life Extension Strategies for Therapeutic Peptides and Proteins.
Current pharmaceutical design, Issue 41, Vol. 24, 4932-4946
DOI: 10.2174/1381612825666190206105232, PubMed: 30727869

Kyriakou E, Schmidt S, Dodd GT, Pfuhlmann K, Simonds SE, Lenhart D, Geerlof A, Schriever SC, De Angelis M, Schramm KW, Plettenburg O, Cowley MA, Tiganis T, Tschöp MH, Pfluger PT, Sattler M, Messias AC (2018)
Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus.
Journal of medicinal chemistry, Issue 24, Vol. 61, 11144-11157
DOI: 10.1021/acs.jmedchem.8b01224, PubMed: 30525586

Kalel VC, Mäser P, Sattler M, Erdmann R, Popowicz GM (2018)
Come, sweet death: targeting glycosomal protein import for antitrypanosomal drug development.
Current opinion in microbiology, Vol. 46, 116-122
DOI: 10.1016/j.mib.2018.11.003, PubMed: 30481613

Weber B, Hora M, Kazman P, Göbl C, Camilloni C, Reif B, Buchner J (2018)
The Antibody Light-Chain Linker Regulates Domain Orientation and Amyloidogenicity.
Journal of molecular biology, Issue 24, Vol. 430, 4925-4940
DOI: 10.1016/j.jmb.2018.10.024, PubMed: 30414962

Fuenzalida-Werner JP, Janowski R, Mishra K, Weidenfeld I, Niessing D, Ntziachristos V, Stiel AC (2018)
Crystal structure of a biliverdin-bound phycobiliprotein: Interdependence of oligomerization and chromophorylation.
Journal of structural biology, Issue 3, Vol. 204, 519-522
DOI: 10.1016/j.jsb.2018.09.013, PubMed: 30287387

Essig K, Kronbeck N, Guimaraes JC, Lohs C, Schlundt A, Hoffmann A, Behrens G, Brenner S, Kowalska J, Lopez-Rodriguez C, Jemielity J, Holtmann H, Reiche K, Hackermüller J, Sattler M, Zavolan M, Heissmeyer V (2018)
Roquin targets mRNAs in a 3'-UTR-specific manner by different modes of regulation.
Nature communications, Issue 1, Vol. 9, 3810
DOI: 10.1038/s41467-018-06184-3, PubMed: 30232334

Weber B, Brandl MJ, Pulido Cendales MD, Berner C, Pradhan T, Feind GM, Zacharias M, Reif B, Buchner J (2018)
A single residue switch reveals principles of antibody domain integrity.
The Journal of biological chemistry, Issue 44, Vol. 293, 17107-17118
DOI: 10.1074/jbc.RA118.005475, PubMed: 30228183

Pfuhlmann K, Schriever SC, Baumann P, Kabra DG, Harrison L, Mazibuko-Mbeje SE, Contreras RE, Kyriakou E, Simonds SE, Tiganis T, Cowley MA, Woods SC, Jastroch M, Clemmensen C, De Angelis M, Schramm KW, Sattler M, Messias AC, Tschöp MH, Pfluger PT (2018)
Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1.
Diabetes, Issue 11, Vol. 67, 2456-2465
DOI: 10.2337/db18-0146, PubMed: 30158241

Tošner Z, Sarkar R, Becker-Baldus J, Glaubitz C, Wegner S, Engelke F, Glaser SJ, Reif B (2018)
Overcoming Volume Selectivity of Dipolar Recoupling in Biological Solid-State NMR Spectroscopy.
Angewandte Chemie (International ed. in English), Issue 44, Vol. 57, 14514-14518
DOI: 10.1002/anie.201805002, PubMed: 29989288

Cristóvão JS, Morris VK, Cardoso I, Leal SS, Martínez J, Botelho HM, Göbl C, David R, Kierdorf K, Alemi M, Madl T, Fritz G, Reif B, Gomes CM (2018)
The neuronal S100B protein is a calcium-tuned suppressor of amyloid-β aggregation.
Science advances, Issue 6, Vol. 4, eaaq1702
DOI: 10.1126/sciadv.aaq1702, PubMed: 29963623

Brenke JK, Popowicz GM, Schorpp K, Rothenaigner I, Roesner M, Meininger I, Kalinski C, Ringelstetter L, R'kyek O, Jürjens G, Vincendeau M, Plettenburg O, Sattler M, Krappmann D, Hadian K (2018)
Targeting TRAF6 E3 ligase activity with a small-molecule inhibitor combats autoimmunity.
The Journal of biological chemistry, Issue 34, Vol. 293, 13191-13203
DOI: 10.1074/jbc.RA118.002649, PubMed: 29950522

Miehling J, Goricanec D, Hagn F (2018)
A Split-Intein-Based Method for the Efficient Production of Circularized Nanodiscs for Structural Studies of Membrane Proteins.
Chembiochem : a European journal of chemical biology, Issue 18, Vol. 19, 1927-1933
DOI: 10.1002/cbic.201800345, PubMed: 29947468

Kooshapur H, Choudhury NR, Simon B, Mühlbauer M, Jussupow A, Fernandez N, Jones AN, Dallmann A, Gabel F, Camilloni C, Michlewski G, Caceres JF, Sattler M (2018)
Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1.
Nature communications, Issue 1, Vol. 9, 2479
DOI: 10.1038/s41467-018-04871-9, PubMed: 29946118

Kazokaitė J, Niemans R, Dudutienė V, Becker HM, Leitāns J, Zubrienė A, Baranauskienė L, Gondi G, Zeidler R, Matulienė J, Tārs K, Yaromina A, Lambin P, Dubois LJ, Matulis D (2018)
Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells.
Oncotarget, Issue 42, Vol. 9, 26800-26816
DOI: 10.18632/oncotarget.25508, PubMed: 29928486

Charlier C, Courtney JM, Alderson TR, Anfinrud P, Bax A (2018)
Monitoring ¹⁵N Chemical Shifts During Protein Folding by Pressure-Jump NMR.
Journal of the American Chemical Society, Issue 26, Vol. 140, 8096-8099
DOI: 10.1021/jacs.8b04833, PubMed: 29923716

von Neubeck B, Gondi G, Riganti C, Pan C, Parra Damas A, Scherb H, Ertürk A, Zeidler R (2018)
An inhibitory antibody targeting carbonic anhydrase XII abrogates chemoresistance and significantly reduces lung metastases in an orthotopic breast cancer model in vivo.
International journal of cancer, Issue 8, Vol. 143, 2065-2075
DOI: 10.1002/ijc.31607, PubMed: 29786141

Iuso A, Wiersma M, Schüller HJ, Pode-Shakked B, Marek-Yagel D, Grigat M, Schwarzmayr T, Berutti R, Alhaddad B, Kanon B, Grzeschik NA, Okun JG, Perles Z, Salem Y, Barel O, Vardi A, Rubinshtein M, Tirosh T, Dubnov-Raz G, Messias AC, Terrile C, Barshack I, Volkov A, Avivi C, Eyal E, Mastantuono E, Kumbar M, Abudi S, Braunisch M, Strom TM, Meitinger T, Hoffmann GF, Prokisch H, Haack TB, Brundel BJJM, Haas D, Sibon OCM, Anikster Y (2018)
Mutations in PPCS, Encoding Phosphopantothenoylcysteine Synthetase, Cause Autosomal-Recessive Dilated Cardiomyopathy.
American journal of human genetics, Issue 6, Vol. 102, 1018-1030
DOI: 10.1016/j.ajhg.2018.03.022, PubMed: 29754768

Tretter JY, Schorpp K, Luxenburger E, Trambauer J, Steiner H, Hadian K, Gires O, Niessing D (2018)
A high-content screen for small-molecule regulators of epithelial cell-adhesion molecule (EpCAM) cleavage yields a robust inhibitor.
The Journal of biological chemistry, Issue 23, Vol. 293, 8994-9005
DOI: 10.1074/jbc.RA118.002776, PubMed: 29700109

Hofweber M, Hutten S, Bourgeois B, Spreitzer E, Niedner-Boblenz A, Schifferer M, Ruepp MD, Simons M, Niessing D, Madl T, Dormann D (2018)
Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.
Cell, Issue 3, Vol. 173, 706-719.e13
DOI: 10.1016/j.cell.2018.03.004, PubMed: 29677514

Ghosh D, Koch U, Hadian K, Sattler M, Tetko IV (2018)
Luciferase Advisor: High-Accuracy Model To Flag False Positive Hits in Luciferase HTS Assays.
Journal of chemical information and modeling, Issue 5, Vol. 58, 933-942
DOI: 10.1021/acs.jcim.7b00574, PubMed: 29667823

Fiedler L, Kellner M, Oos R, Böning G, Ziegler S, Bartenstein P, Zeidler R, Gildehaus FJ, Lindner S (2018)
Fully Automated Production and Characterization of ⁶⁴ Cu and Proof-of-Principle Small-Animal PET Imaging Using ⁶⁴ Cu-Labelled CA XII Targeting 6A10 Fab.
ChemMedChem, Issue 12, Vol. 13, 1230-1237
DOI: 10.1002/cmdc.201800130, PubMed: 29667369

Charlier C, Alderson TR, Courtney JM, Ying J, Anfinrud P, Bax A (2018)
Study of protein folding under native conditions by rapidly switching the hydrostatic pressure inside an NMR sample cell.
Proceedings of the National Academy of Sciences of the United States of America, Issue 18, Vol. 115, E4169-E4178
DOI: 10.1073/pnas.1803642115, PubMed: 29666248

Rutz DA, Luo Q, Freiburger L, Madl T, Kaila VRI, Sattler M, Buchner J (2018)
A switch point in the molecular chaperone Hsp90 responding to client interaction.
Nature communications, Issue 1, Vol. 9, 1472
DOI: 10.1038/s41467-018-03946-x, PubMed: 29662162

Sutandy FXR, Ebersberger S, Huang L, Busch A, Bach M, Kang HS, Fallmann J, Maticzka D, Backofen R, Stadler PF, Zarnack K, Sattler M, Legewie S, König J (2018)
In vitro iCLIP-based modeling uncovers how the splicing factor U2AF2 relies on regulation by cofactors.
Genome research, Issue 5, Vol. 28, 699-713
DOI: 10.1101/gr.229757.117, PubMed: 29643205

Barbet-Massin E, van der Sluis E, Musial J, Beckmann R, Reif B (2018)
Reconstitution of Isotopically Labeled Ribosomal Protein L29 in the 50S Large Ribosomal Subunit for Solution-State and Solid-State NMR.
Methods in molecular biology (Clifton, N.J.), Vol. 1764, 87-100
DOI: 10.1007/978-1-4939-7759-8_6, PubMed: 29605910

Gärtner K, Battke C, Dünzkofer J, Hüls C, von Neubeck B, Kellner MK, Fiestas E, Fackler S, Lang S, Zeidler R (2018)
Tumor-derived extracellular vesicles activate primary monocytes.
Cancer medicine, Issue 5, Vol. 7, 2013-2020
DOI: 10.1002/cam4.1465, PubMed: 29601673

Kovalishyn V, Grouleff J, Semenyuta I, Sinenko VO, Slivchuk SR, Hodyna D, Brovarets V, Blagodatny V, Poda G, Tetko IV, Metelytsia L (2018)
Rational design of isonicotinic acid hydrazide derivatives with antitubercular activity: Machine learning, molecular docking, synthesis and biological testing.
Chemical biology & drug design, Issue 1, Vol. 92, 1272-1278
DOI: 10.1111/cbdd.13188, PubMed: 29536635

Tomala MD, Magiera-Mularz K, Kubica K, Krzanik S, Zieba B, Musielak B, Pustula M, Popowicz GM, Sattler M, Dubin G, Skalniak L, Holak TA (2018)
Identification of small-molecule inhibitors of USP2a.
European journal of medicinal chemistry, Vol. 150, 261-267
DOI: 10.1016/j.ejmech.2018.03.009, PubMed: 29529503

Asami S, Kallies W, Günther JC, Stavropoulou M, Glaser SJ, Sattler M (2018)
Ultrashort Broadband Cooperative Pulses for Multidimensional Biomolecular NMR Experiments.
Angewandte Chemie (International ed. in English), Issue 44, Vol. 57, 14498-14502
DOI: 10.1002/anie.201800220, PubMed: 29508496

Raltchev K, Pipercevic J, Hagn F (2018)
Production and Structural Analysis of Membrane-Anchored Proteins in Phospholipid Nanodiscs.
Chemistry (Weinheim an der Bergstrasse, Germany), Issue 21, Vol. 24, 5493-5499
DOI: 10.1002/chem.201800812, PubMed: 29457664

Close W, Neumann M, Schmidt A, Hora M, Annamalai K, Schmidt M, Reif B, Schmidt V, Grigorieff N, Fändrich M (2018)
Physical basis of amyloid fibril polymorphism.
Nature communications, Issue 1, Vol. 9, 699
DOI: 10.1038/s41467-018-03164-5, PubMed: 29453354

Rehage N, Davydova E, Conrad C, Behrens G, Maiser A, Stehklein JE, Brenner S, Klein J, Jeridi A, Hoffmann A, Lee E, Dianzani U, Willemsen R, Feederle R, Reiche K, Hackermüller J, Leonhardt H, Sharma S, Niessing D, Heissmeyer V (2018)
Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA.
Nature communications, Issue 1, Vol. 9, 299
DOI: 10.1038/s41467-017-02582-1, PubMed: 29352114

Franko A, Rodriguez Camargo DC, Böddrich A, Garg D, Rodriguez Camargo A, Rathkolb B, Janik D, Aichler M, Feuchtinger A, Neff F, Fuchs H, Wanker EE, Reif B, Häring HU, Peter A, Hrabě de Angelis M (2018)
Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice.
Scientific reports, Issue 1, Vol. 8, 1116
DOI: 10.1038/s41598-017-18807-8, PubMed: 29348618

Colaluca IN, Basile A, Freiburger L, D'Uva V, Disalvatore D, Vecchi M, Confalonieri S, Tosoni D, Cecatiello V, Malabarba MG, Yang CJ, Kainosho M, Sattler M, Mapelli M, Pece S, Di Fiore PP (2018)
A Numb-Mdm2 fuzzy complex reveals an isoform-specific involvement of Numb in breast cancer.
The Journal of cell biology, Issue 2, Vol. 217, 745-762
DOI: 10.1083/jcb.201709092, PubMed: 29269425

Hagn F, Nasr ML, Wagner G (2018)
Assembly of phospholipid nanodiscs of controlled size for structural studies of membrane proteins by NMR.
Nature protocols, Issue 1, Vol. 13, 79-98
DOI: 10.1038/nprot.2017.094, PubMed: 29215632

Reijnders MRF, Janowski R, Alvi M, Self JE, van Essen TJ, Vreeburg M, Rouhl RPW, Stevens SJC, Stegmann APA, Schieving J, Pfundt R, van Dijk K, Smeets E, Stumpel CTRM, Bok LA, Cobben JM, Engelen M, Mansour S, Whiteford M, Chandler KE, Douzgou S, Cooper NS, Tan EC, Foo R, Lai AHM, Rankin J, Green A, Lönnqvist T, Isohanni P, Williams S, Ruhoy I, Carvalho KS, Dowling JJ, Lev DL, Sterbova K, Lassuthova P, Neupauerová J, Waugh JL, Keros S, Clayton-Smith J, Smithson SF, Brunner HG, van Hoeckel C, Anderson M, Clowes VE, Siu VM, Ddd Study T, Selber P, Leventer RJ, Nellaker C, Niessing D, Hunt D, Baralle D (2018)
PURA syndrome: clinical delineation and genotype-phenotype study in 32 individuals with review of published literature.
Journal of medical genetics, Issue 2, Vol. 55, 104-113
DOI: 10.1136/jmedgenet-2017-104946, PubMed: 29097605

Alderson TR, Lee JH, Charlier C, Ying J, Bax A (2018)
Propensity for cis-Proline Formation in Unfolded Proteins.
Chembiochem : a European journal of chemical biology, Issue 1, Vol. 19, 37-42
DOI: 10.1002/cbic.201700548, PubMed: 29064600

Niessing D, Jansen RP, Pohlmann T, Feldbrügge M (2018)
mRNA transport in fungal top models.
Wiley interdisciplinary reviews. RNA, Issue 1, Vol. 9
DOI: 10.1002/wrna.1453, PubMed: 28994236

Supekar S, Papageorgiou AC, Gemmecker G, Peltzer R, Johansson MP, Tripsianes K, Sattler M, Kaila VRI (2018)
Conformational Selection of Dimethylarginine Recognition by the Survival Motor Neuron Tudor Domain.
Angewandte Chemie (International ed. in English), Issue 2, Vol. 57, 486-490
DOI: 10.1002/anie.201708233, PubMed: 28980372

Kovalishyn V, Abramenko N, Kopernyk I, Charochkina L, Metelytsia L, Tetko IV, Peijnenburg W, Kustov L (2018)
Modelling the toxicity of a large set of metal and metal oxide nanoparticles using the OCHEM platform.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 112, 507-517
DOI: 10.1016/j.fct.2017.08.008, PubMed: 28802948

Withnall M, Chen H, Tetko IV (2018)
Matched Molecular Pair Analysis on Large Melting Point Datasets: A Big Data Perspective.
ChemMedChem, Issue 6, Vol. 13, 599-606
DOI: 10.1002/cmdc.201700303, PubMed: 28650584